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Examination of the variations between microcrystalline and nano-hydroxyapatite for defense towards dental caries and remineralizing the tooth.
A development I’ve observed in current months is that useful docs and organic dentists are more and more recommending merchandise that include nano-hydroxyapatite to their sufferers.
What’s hydroxyapatite, or “HA” as it’s generally abbreviated?
HA is sort of merely floor bone with solely the moisture extracted.
Nothing else is added or eliminated.
Hydroxyapatite Protects and Remineralizes Tooth
Analysis revealed within the scientific literature convincingly demonstrates that hydroxyapatite gives extremely efficient safety towards dental caries. It additionally gives advantages for tooth remineralization. (1, 2)
In truth, the analysis clearly reveals that hydroxyapatite’s protecting results on the tooth are pretty much as good or higher than fluoride.
Thus, for these wishing to keep away from the organic harm of fluoride publicity, hydroxyapatite is a superb and protected various.
The query is, what sort?
Is the nano-hydroxyapatite that’s in a rising proportion of fluoride-free, remineralizing oral care merchandise the best way to go?
Let’s have a look.
Microcrystalline vs Nano
Microcrystalline hydroxyapatite is the type of dehydrated bone that’s floor to as nice a particle dimension as might be carried out mechanically.
Nano-hydroxyapatite is one thing else totally…the particle dimension is massively smaller than the microcrystallized type.
How a lot smaller?
“Nano” is 1000 occasions smaller than “micro”. (3)
In truth, nanoparticles are so small that they’ll simply breach the partitions of cells and even the nuclear membrane inside a single cell itself…the place DNA is positioned.
Advantages and Dangers
Whereas microcrystalline hydroxyapatite is 100% protected to be used in oral care merchandise (right here’s the place I get mine), it’s best to keep away from the nano model.
Analysis thus far means that there are dangers for mutations to DNA. This happens from the breaching of the nanoparticles previous the nuclear membranes of particular person cells.
Please word that I’m not questioning the analysis on nano-hydroxyapatite.
The advantages are fairly compelling and credible in that it’s certainly useful in defending towards cavities in addition to for remineralization functions.
Nevertheless, there may be RISK in utilizing nano-hydroxyapatite as effectively. Some various practitioners are glossing over these risks by recommending merchandise containing them.
In brief, progress within the evaluation of well being dangers from nanoparticles, aka “nano-toxicology”, is being far outstripped by the fast advances in nano-technology itself. (4)
Thus, sensible shoppers could be effectively suggested to make use of warning with merchandise containing nano-hydroxyapatite else they will find yourself as guinea pigs for this know-how.
Whereas anticipated advantages from nano-hydroxyapatite could happen, the uncomfortable side effects might be far worse than tooth decay!
A number of the dangers from nanoparticles are already recognized within the literature. Dr. Al Danenberg DDS warns about these risks which embrace cytotoxicity, harm, and mutations to mobile DNA. (5)
This happens because of the breaching of the nuclear membrane (not simply the cell membrane as mentioned within the pro-nanoparticle analysis!).
Nano-Hydroxyapatite Is Not Pure
In brief, the place microcrystalline hydroxyapatite is a pure substance with a particle dimension that the physique acknowledges and may take care of, nano-hydroxyapatite is just not.
Nano-hydroxyapatite is the artificial type of hydroxyapatite with confirmed advantages however loads of unknown dangers to the integrity of your DNA.
The particle dimension of nano-hydroxyapatite (or any nanoparticle for that matter) is so tiny that it simply breaches the blood-brain barrier in addition to the nuclear member defending the DNA of each cell.
Abstract
In closing, you will need to know that whereas research present nano-hydroxyapatite to be efficacious, it has not been confirmed protected.
Thus, should you want to get pleasure from the advantages of remineralizing hydroxyapatite in your oral care merchandise, follow firms that solely use the microcrystalline type.
As of this writing, I solely know of 1 firm that provides some of these merchandise.
That is the hydroxyapatite tooth powder that I exploit and suggest that incorporates the protected particle (non-nano) type.
Do you favor to make your personal tooth powder?
This bag of microcrystalline hydroxyapatite is ideal for the DIY oral care recipes you make at residence.
Lastly, what to do with practitioners who’re recommending nano-hydroxyapatite merchandise for you or your youngsters?
If it have been me on this state of affairs, I’d politely say no.
The medical analysis merely doesn’t help the protection of nanoparticles for human DNA.
(1, 3) Nano or No-No? Hydroxyapatite Particle Dimension Issues…
(2) Scientific sources of Hydroxyapatite for Oral Well being
(4) Nano-technology and Nano-toxicology
(5) Managing Well being by Minding Your Intestine (and Mouth) Microbiome (beginning at 1:11)