A number of modalities efficient in geographic atrophy prognosis

Date:


October 20, 2024

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CHICAGO — Totally different imaging modalities are efficient for the prognosis of geographic atrophy, in keeping with a speaker on the American Academy of Ophthalmology assembly.

SriniVas R. Sadda, MD, mentioned over time, flash colour fundus images has been the gold normal for geographic atrophy (GA) prognosis. Nonetheless, newer modalities have gotten simpler.



Retina

Totally different imaging modalities are efficient for the prognosis of GA.
Picture: Adobe Inventory.

“We’ve a definition for atrophy of a sharply demarcated area with depigmentation and elevated visibility of choroidal blood vessels,” he mentioned. “That served us very nicely for various totally different research. However the issue is that this requires good stereopsis, and typically we don’t have adequate distinction.”

Which means colour fundus pictures aren’t all the time sensible, notably for scientific trials, Sadda mentioned.

Blue-light fundus autofluorescence, a newer know-how, has been a useful gizmo in scientific trials as a result of it offers sharper distinction. Nonetheless, blue gentle will be uncomfortable for some sufferers, and repeat use in sufferers with atrophic macular illness will be poisonous, Sadda mentioned.

Sadda mentioned retina imaging is within the period of confocal colour, inexperienced fundus autofluorescence and OCT. Research have proven that these modalities are efficient for the prognosis of GA, in addition to for measuring development

Though microperimetry is just not one of the best device for the preliminary prognosis of GA, Sadda mentioned it may be useful to trace practical development.

As extra therapies turn into out there for GA, Sadda mentioned technological advances will assist handle sufferers and facilitate the totally different imaging strategies.

“Automated quantification enabled by AI instruments is actually going to make a distinction on this new period,” he mentioned.

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