Actual-world information present visible acuity good thing about faricimab in neovascular AMD

Date:


January 21, 2025

1 min learn


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Key takeaways:

  • Visible acuity improved in treatment-naive sufferers and was steady in beforehand handled sufferers.
  • Sufferers additionally skilled a discount in central subfield thickness.

KOLOA, Hawaii — Faricimab helped enhance imaginative and prescient in beforehand untreated sufferers with neovascular age-related macular degeneration, based on a real-world research introduced at Retina 2025.

Ferhina S. Ali, MD, MPH, introduced an replace on scientific outcomes from FARETINA-AMD, a retrospective real-world research that used information from the IRIS Registry.



Ferhina S. Ali, MD, MPH

Picture: Eamon N. Dreisbach


The research included sufferers with a prognosis of neovascular AMD who obtained at the very least one faricimab injection between February 2022 and March 2023. All sufferers had at the very least 12 months of medical information earlier than beginning faricimab and at the very least 12 months of follow-up information, and visible acuity measurements have been required, Ali stated.

The research included information from 2,025 beforehand untreated sufferers and 22,253 sufferers who had beforehand undergone remedy.

Amongst sufferers within the treatment-naive group, imply visible acuity on the seventh faricimab injection was 62 letters in contrast with 57.3 letters at baseline. Within the beforehand handled group, sufferers maintained visible acuity of 62 letters after the seventh injection vs. 61.7 letters at baseline, Ali stated.

In a subgroup evaluation, sufferers in each teams skilled discount in imply central subfield thickness after the seventh faricimab injection in contrast with baseline (253.7 µm vs. 307.6 µm and 270.7 µm vs. 293.1 µm, respectively).

“We’re wanting on the largest pattern of sufferers who’ve been handled with faricimab because it grew to become out there,” Ali stated. “Sufferers introduced on common with good imaginative and prescient. We noticed imaginative and prescient that improved within the treatment-naive eyes and stability of imaginative and prescient in beforehand handled.”

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