NOW (Bloomingdale, IL) continued its award-winning high quality testing program with a survey of 25 completely different model samples of methylcobalamin (methyl B12) bought on Amazon in January 2025.
Methyl B12 was chosen due to its excessive value and potential failure of its efficiency label declare. The outcomes as soon as once more recognized manufacturers not assembly label claims, however fewer than different dietary supplements NOW examined prior to now. All of the samples have been analyzed utilizing high-performance liquid chromatography (HPLC).
This spherical of testing highlighted that as a result of “inherent complexity” of testing vitamin B12, even third-party testing labs might not have the ability to produce constant outcomes, NOW mentioned.
In keeping with NOW, of the 23 manufacturers (not counting NOW’s two merchandise), 11 manufacturers exceeded their label claims with six testing above 120 %, 12 manufacturers examined beneath One hundred pc with three testing between 90-One hundred pc and three testing at 0-1 % efficiency.
The liquid and gummy types have been much less steady and more durable to investigate precisely in comparison with tablets and capsules. Just one product met efficiency whereas others ranged from 1 % to 105 %, NOW mentioned.
“Testing vitamin B12 is inherently difficult as a result of instability of methylcobalamin and the problem in acquiring constant outcomes throughout varied matrices and dosage types. Contract laboratories typically battle with sustaining customary stability and correct analyte restoration, contributing to the variability noticed on this examine. Our inner knowledge spotlight the business’s want for extra sturdy testing strategies and high quality management measures,” NOW mentioned.
For extra info, go to www.nowfoods.com.
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