Unlock Your Physique’s Therapeutic Potential: The Sport-Altering X-Cells

July 16, 2024

Continual ache that simply will not go away… regenerative remedies that value 1000’s of {dollars}, but solely supply momentary reduction… outdated accidents that progressively worsen over time…

For those who’re uninterested in this infinite cycle of frustration and disappointment, you are not alone. However what if there was a solution to break away from this sample and unlock your physique’s true therapeutic potential?

Whereas it’d sound like science fiction, there is a new, cutting-edge revolutionary remedy that may supercharge your physique’s therapeutic talents by regenerating broken tissues, doubtlessly reversing years of wear and tear and tear and turbo-boosting your longevity within the course of.

Whether or not you are battling joint ache that is maintaining you out of your favourite actions, fighting a neurological situation that is affecting your high quality of life, or just wanting to show again the clock on getting old, X cells might be the game-changing answer you’ve got been trying to find.

On this visitor publish, written by famend well being and longevity knowledgeable Dr. John Lieurance, you will uncover how this breakthrough remedy is outperforming conventional stem cell remedies, providing hope for circumstances starting from arthritis to Alzheimer’s.

Dr. John Lieurance is a naturopathic doctor and chiropractic neurologist who has devoted over twenty years to pioneering breakthroughs within the fields of regenerative drugs and pure well being. Because the founding father of Superior Rejuvenation and the developer of a number of proprietary remedies, Dr. Lieurance has a profound understanding of learn how to harness the physique’s innate therapeutic powers to optimize well being and reverse power circumstances. He’s additionally an excellent pal of mine and a multi-time visitor on my podcast (you could find the podcast episodes he is been featured on right here, right here, right here, and right here).

With in depth expertise in therapies like stem cell remedy, PRP remedy, and ozone remedy, Dr. Lieurance is a real innovator on the forefront of integrative drugs. His mission is to empower people with cutting-edge information and coverings that facilitate profound well being transformations.

Heads up: Dr. Lieurance can be diving deep into among the most superior and potent methods in pure therapeutic, a lot of which outpace typical medical approaches. You will need to soak up each little bit of knowledge he shares on this article, so if you cannot get by it all of sudden, it can save you it and return to it later — that is invaluable information you will need to revisit!

Bear in mind, you do not have to accept band-aid options or resign your self to a way forward for declining well being. Learn on to learn the way X cells might be the important thing to unlocking your physique’s innate therapeutic potential and reclaiming the colourful, pain-free life you deserve.

Key “X Cell” Takeaways You will Uncover in This Article

• X cells, derived from adipose tissue of younger, wholesome donors, symbolize a major development in stem cell remedy, outperforming conventional perinatal stem cells in numerous facets.
• X cells have superior survival charges (3–10 weeks) in comparison with perinatal stem cells (1–2 hours), permitting for longer-lasting regenerative results.
• The “complete meals” strategy of X cells, containing a various array of stem cell sorts and supporting elements, supplies a synergistic therapeutic impact just like the entourage impact seen in hashish therapeutics. 
• X cells present promise in treating a variety of circumstances, together with orthopedic points, neurological issues, autoimmune ailments, and age-related decline.
• “Stem-hacking” strategies (which you’ll be able to uncover extra about right here), such because the Pink, Blue, O2 protocol (combining pink gentle remedy, methylene blue, and hyperbaric oxygen), can improve the effectiveness of stem cell remedies. 
• Focused vitamins like melatonin (you’ll be able to click on right here to affix Dr. Lieurance’s MitoZen Membership, the place you will get the identical excessive dose of melatonin that I exploit), CoQ10, and fucoidan can help stem cell survival and performance, doubtlessly enhancing the general success of stem cell remedy.

X Cells: The “Rolls Royce” of Stem Cells (by Dr. John Lieurance)

After working within the area of regenerative drugs for over 25 years, I’ve seen many stem cell functions and quite a few varieties of stem cells. All of them have their distinctive traits, and so they all have their drawbacks. However I’ve lastly discovered a kind that adjustments the sport and surpasses all the remaining. 

Stem cells could be autologous (from your individual physique) or allogeneic (from a supply outdoors your physique). The most typical autologous stem cells are from bone marrow or adipose tissue (extra generally often called physique fats). As a result of utilizing autologous stem cells is extra concerned and extra invasive, the vast majority of clinics use allogeneic sources from perinatal tissue or exosomes (tiny vesicles secreted from stem cells that activate a rejuvenating impact) derived from these perinatal tissues. 

Initially, my clinic, Superior Rejuvenation, used stem cells and exosomes from perinatal sources for years with respectable outcomes. Till not too long ago, I thought of them to be the best choice for an off-the-shelf allogeneic stem cell. A few yr in the past, nevertheless, a brand new possibility turned accessible that I’ve discovered to be way more highly effective. 

Introducing X Cells: The Epitome of Regenerative Potential

X cells, named for his or her “further” energy and viability, are derived from adipose tissue donated by younger, wholesome people, representing a paradigm shift in regenerative drugs.

Comprising roughly 10 several types of stem cells, X cells supply a multifaceted strategy to tissue restore and regeneration.

One of many main constituents of X cells are adipose-derived stem cells (ADSCs) — or stem cells from fats — which have emerged as promising candidates for treating orthopedic, neurologic, and autoimmune circumstances. 

Amongst a myriad of different functions, X cells even have an enhanced capacity to provide each endothelial cells and regenerate nerves, which makes them a superb selection for treating hair loss, pores and skin rejuvenation, and sexual rejuvenation, leading to higher orgasms for girls and an finish to erectile dysfunction in males. 

After cautious examination of the analysis you will discover cited all through this text, I strongly imagine X cells is perhaps the best choice for anybody searching for regeneration in orthopedic, neurologic, and autoimmune circumstances. 

The prevalence of X cells stems from a number of distinctive traits:

• Robust survival: X cells are resilient and may survive in harsh environments, akin to inside broken tissues the place we’d like them most. They’ll dwell from 3–10 weeks, whereas most perinatal stem cell sorts solely survive 1–2 hours (if in any respect!).
• Quick-acting: X cells differentiate 4 instances quicker than perinatal mesenchymal stem cells. This implies they will begin working quicker to regenerate your physique.
• Vascularization: X cells are superior at producing endothelial cells at a way more speedy fee. Meaning extra blood provide to the brand new cells and tissues so the physique can herald all the mandatory oxygen and vitamins to create cartilage, nerve tissue, ligaments, and muscle groups.
• Inhibit most cancers formation: Muse cells contained in X cells inhibit most cancers and teratoma formation, making them far superior to different choices.
• Immune tolerance: X cells have the potential to determine immune tolerance.

A Various Array of Regenerative Cells in X Cells 

The wealthy reservoir of regenerative vitamins current in adipose tissue underscores its significance in regenerative drugs. Analogous to complete meals that provide superior dietary worth in comparison with artificial counterparts, adipose tissue harbors a various array of stem cells important for tissue restore and regeneration.

The idea of the “entourage impact,” widely known within the context of hashish therapeutics, elucidates the synergistic interactions amongst numerous elements to produce enhanced therapeutic outcomes. 

Equally, adipose tissue serves as a reservoir of regenerative “complete meals” sources, comprising fibroblasts, ADSCs, Muse stem cells, endothelial progenitor cells, and supporting progress elements, collectively orchestrating a symphony of therapeutic processes. That’s why I name our bone marrow and adipose tissue the “complete meals” of regenerative drugs.

Our clinic began utilizing each fats and bone marrow in stem cell remedies in 2005, and I haven’t discovered something that creates a regenerative final result as highly effective and sturdy. I’ve seen circumstances a decade or extra post-treatment and sufferers are nonetheless pain-free and dwelling their greatest life.

X cells are a posh combine containing lots of of stem cell sorts, progress elements, and supporting cells, together with:

• Mesenchymal stem cells (MSCs): MSCs are multipotent stromal cells that may differentiate into quite a lot of cell sorts, together with bone cells (osteoblasts), cartilage cells (chondrocytes), fats cells (adipocytes), and others. They’re present in numerous tissues, together with bone marrow, adipose tissue, and umbilical wire tissue. MSCs play a vital function in tissue restore, irritation regulation, and immune modulation, making them useful in regenerative drugs and therapeutic functions. They usually make up 6–12% of X cells.  
• Hematopoietic stem cells: These are immature cells that may turn into all varieties of blood cells, which in flip permit stem cells to engraft higher, enhancing survivability.
• Endothelial progenitor cells (EPCs): EPCs create endothelial cells which help the creation of recent blood vessels. This permits the cells to get vitamins that help survivability.
• Supporting stem cells: These embody fibroblasts, endothelial cells, pericytes, and immune cells. They play a vital function within the general operate of X cells by offering structural help, secreting progress elements, and modulating the immune response. 
• Muse cells: Muse cells are a stress-tolerant inhabitants of stem cells present in each bone marrow and adipose tissue. They’re pluripotent, that means they will shapeshift into any cell line. They’ll additionally endure hostile environments, helping their survival in broken or injured tissues. They help tissues concerned within the mind and neurological facets of our well being in addition to tissues associated to the lungs, thyroid, and pancreas. Moreover, Muse cells have inherent immunomodulatory properties that help calming down irritation and autoimmune circumstances, along with contributing to tissue regeneration and restore.
• Preadipocytes: Preadipocytes are probably the most considerable cell kind within the collective of cells within the adipose tissue. Current proof means that this cell shares lots of the similar phenotypic markers and traits of MSCs, implicating its involvement in regeneration.

There are actually lots of of corporations producing numerous culture-expanded stem cells that are grown in a lab to make duplicates of a selected cell. They’re usually from placental origin or perinatal tissue.

My perspective is that it’s like white bread, devoid of the gamut of supporting and synergistic cell strains that present therapeutic. They lack the majesty in our bone and fats put there by creation itself. 

Some corporations utilizing these “white bread” stem cells have began utilizing gene remedy to activate cells to turn into sure cell sorts. It definitely sounds horny and instructions a better value level. However is this sort of gene manipulation actually mandatory when nature has already offered our our bodies with the whole lot they should heal and regenerate? 

Unraveling the Mysteries of Stem Cell Isolation

Adipose-derived stem cells are usually remoted from the stromal vascular fraction (SVF), or assortment of cells inside the adipose tissue. The SVF is taken into account the “complete meals” of adipose tissue. Analysis evaluating the isolation of ADSCs versus combining them with the SVF has concluded that SVF remedy confirmed superior, statistically vital outcomes in comparison with ADSC remedy alone.

One other research discovered a bonus of SVF over ADSCs in two basic areas. First, the range of cells could also be responsible for the higher therapeutic outcomes noticed, not not like the entourage impact talked about earlier. Second, SVF is obtained with minimal contact with reagents, making it comparatively safer.

Not like typical isolation strategies that contain chemical processing, X cells are meticulously processed utilizing gravity alone, preserving their innate regenerative properties.

Clearly, with bone marrow and adipose, nature has packaged the correct assortment of regenerative properties completely, and X cells now appear to be an ideal instance of that.

Evaluating X Cells to Perinatal Stem Cells 

Higher Survival 

There may be an abundance of literature that helps the vastly superior survival fee and regenerative potential of X cells in comparison with perinatal stem cells. 

In a nutshell, X cells survive longer, in order that they work longer and proceed the regeneration course of for weeks after implantation. Different stem cell sources, against this, die rapidly.  

Perinatal tissues have such poor survival, they could solely final 1 hour. Research have proven that allogeneic stem cells from perinatal tissues face challenges in long-term survival and immunogenicity after transplantation, impacting their therapeutic efficacy. That’s an enormous distinction in comparison with the three weeks that X cells can survive. In a single research, X cells have been nonetheless current and alive 10 weeks later!

Perinatal stem cells have additionally been proven to be delicate to harsh environments as soon as transplanted. Analysis has proven that engraftment — the flexibility of those stem cells to really work — is weak with perinatal stem cells.

Superior Area of interest Formation 

As soon as stem cells are transplanted right into a joint or one other space of the physique, they face three doable outcomes: they may survive and thrive, they may die, or they may turn into senescent (a everlasting state of sleep).

The area of interest, or the surroundings the cells can be subjected to, is a major consider figuring out the course these cells will take. A distinct segment could be both harsh or hospitable. Perinatal stem cells lack area of interest help as soon as launched into the physique, whereas the stem cell strains contained in X cells are sturdy and resist changing into pressured even when positioned right into a harsh surroundings. 

Many power accidents that stem cell remedy treats require these cells to endure difficult environments. What makes the surroundings harsh is the extent of irritation, which can also be related to oxidation. Analysis has proven that X cells have a excessive probability of survival in high-oxidation environments. They’re merely higher than some other stem cell strains studied. 

Not solely are X cells resilient to harsh environments, however they really have the flexibility to quickly create a extra hospitable surroundings as soon as they’re positioned there. They obtain this by bringing in endothelial cells that create a brand new blood provide, which then brings in vitamins like amino acids and oxygen. X cells additionally produce substances known as progress elements that additional help the growth and differentiation course of. The thought is that the gathering of this “complete meals” mixture of cells permits for speedy improvement of blood provide to start offering vitamins to the stem cells and new tissues they’re creating.

Immune Rejection 

Perinatal stem cells have a excessive immunological rejection fee, which primarily means your immune system kills them. Because of this they trigger extra ache and irritation than X cells. 

Equally, all “cross-sex” umbilical stem cells (these that are positioned within the physique of somebody with a special intercourse than the stem cells originated), have points with engraftment. In these circumstances, engraftment — the method of the stem cells really being assimilated into the remedy space — is doubtful, if it occurs in any respect. 

In an effort to stop graft failure, the perinatal tissue would must be processed in order that the MSCs could be remoted and expanded, producing just one era in a bioreactor. Most corporations do a number of generations of growth for larger yields, however this shortens the telomeres, and thus the cells’ viability and efficiency decline with every era.

Exosomes 

Stem cells not solely migrate to broken tissue and differentiate into numerous cell strains to interchange the broken cells, however additionally they connect in places adjoining to broken cells and launch tiny vesicles known as exosomes. 

Exosomes are tiny packages of RNA. RNA carries data, and these little vesicles carry data from the stem cell. This encourages the broken cells in addition to wholesome cells within the space to enter a regenerative part and start to rebuild broken tissue with new, recent cells and tissue. Finally, it’s your personal cells and tissue that do the restore after the RNA within the exosomes showers the injured or weakened websites within the physique. 

Exosomes launched by stem cells present the first affect for regeneration. Whereas exosome manufacturing is tough to measure because of their extraordinarily small dimension and the truth that their yield is determined by quite a lot of elements, a scientist on this area whom I spoke with steered that each perinatal and ADSC stem cells may produce a median of 17 million exosomes per hour. Meaning a typical perinatal stem cell produces solely 2.5% of what an X cell may create over 3 weeks.

That is 4,000% extra regenerative capacity!

X Cells Clinically 

Mesenchymal stem cells have been profitable in numerous remedies, together with Crohn’s illness and osteoarthritis of the knee. There have been over 200 scientific stem cell trials using X cells, greater than some other stem cell supply to this point. 

X cells are pure, not expanded, and processed with out dimethylsulfoxide (DMSO) or enzymes. Superior Rejuvenation is the primary clinic to make use of X cells for internal ear regeneration, and we plan to start scientific trials quickly based mostly on optimistic outcomes.

X Cells for the Mind and Nerves 

Analysis has proven that the neuroregenerative potential of X cells holds immense promise for treating circumstances akin to a number of sclerosis and neuropathy in addition to selling grownup neurogenesis within the brains of Alzheimer’s sufferers.

X cells are additionally exquisitely delicate to their surroundings, receiving chemical signaling to turn into numerous varieties of nerve cells. Analysis has proven that X cells carry additional vital benefits, as they’ve a bias to turn into mind and nerve tissues.

Stem-Hacking: Biohacking Stem Cell Remedy 

Most circumstances that may be handled utilizing stem cell remedy will also be supported with the synergy of the Pink, Blue, O2 protocol pioneered by my clinic, Superior Rejuvenation. Very like the entourage impact with hashish, this protocol combines modalities that may synergistically help therapeutic.

Listed here are some focused stacks I exploit in my clinic to help stem cell remedy:  

• The Pink, Blue, O2 protocol: It is a synergistic remedy combining pink gentle remedy, methylene blue, and hyperbaric oxygen remedy (HBOT). This professionaltocol additionally consists of different photodynamic substances and cranial remedy by way of endonasal balloon manipulations, which goal to extend oxygen inside the mind by enhancing nasal respiratory (for extra data, you’ll be able to take a look at this podcast). 
• Pink gentle: A number of research have proven laser gentle remedy inside the pink and near-infrapink spectrums to help regenerative drugs and cell remedy. This photobiomodulation will increase X cell survival and gene expression to cut back oxidative stress.
• Methylene blue: Methylene blue could enhance the survival of cells important for central nervous system operate and fight degenerative neurological illness. Methylene blue was additionally present in an Alzheimer’s research to modulate the migratory capability of grownup neural stem cells, enhancing cell mobility. You may click on right here to affix Dr. Lieurance’s Mitozen Membership for entry to the very best methylene blue merchandise!
• HBOT: Research on hyperbaric oxygen present that it will increase stem cell proliferation, the formation of recent blood cells, and healing.

For extra on the Pink, Blue, O2 protocol, you’ll be able to snag a replica of Methylene Blue: Magic Bullet on Amazon (and take a look at our current podcast collectively to find extra about this matter). You can even join an occasion with the three pioneers of the Pink, Blue, O2 protocol — Dr. Jason Sonners, Brian Richards of Sauna House, and myself, on Aug. 23, 2024, in individual in Sarasota in addition to by way of livestream. You may use low cost code BEN10 to avoid wasting 10% on tickets!

Stem-Hacking Focused Vitamins to Help Stem Cell Remedy

Most accidents and dysfunctional organs which might be handled utilizing stem cell remedy have excessive ranges of irritation, oxidative stress, and poor circulation. These so-called area of interest stressors restrict the survivability, differentiation, and general success of stem cell remedy.

Melatonin has been proven to guard stem cells towards oxidative stress in addition to calm irritation, thereby enhancing stem cell survival. One research went as far as to conclude that combining melatonin with stem cell remedy was superior to stem cell remedy alone.

Ben and I’ve recorded a couple of podcast episodes discussing melatonin, significantly larger doses delivered rectally (because of its poor oral absorption). MitoZen’s Sandman line of high-dose melatonin additionally accommodates glutathione, which has additionally been proven to help ADSC survival.

Coenzyme Q10 (CoQ10) has been proven to guard stem cell getting old, and the mechanisms of cell senescence inhibited by CoQ10 have been demonstrated in analysis.

Fucoidan, present in brown algae and seaweed, is taken into account anti-senescent, anti-apoptotic, anti-tumor, anti-inflammatory, and anti-oxidative. Fucoidan enhances the bioavailability of endothelial progenitor cells, improves survival in mesenchymal stem cells, will increase proliferation, and amps up mobile useful properties.

At MitoZen.membership, we mix CoQ10 and fucoidan to make StemZen, a product particularly designed to stop senescence and maximize stem cells.

Methylene blue reduces area of interest stressors and helps the mitochondria in stem cells. MitoZen’s Lumetol Blue could be taken each day to help and improve stem cell remedy. Take a look at the podcast episode Ben and I did on methylene blue right here.

Prolonged fasting additionally releases stem cells within the refeeding part. Utilizing these protocols and solutions can help the survival of those newly launched stem cells. MitoZen.membership has a Quick-Monitor Quick Package which makes use of some of our most helpful merchandise — Lumetol Blue, the StemZen bullet, and high-dose melatonin within the type of the Tremendous Sandman Bullet. Observe this hyperlink to find extra in regards to the Quick-Monitor Quick from MitoZen.membership.

Enhancing the survival fee of implanted stem cells in unfavorable environments utilizing vitamins like melatonin and methylene blue, together with therapies akin to these within the Pink, Blue, O2 protocol, could be key to enhancing the success of stem cell remedy.

Abstract

So, there you’ve it! As you’ve got explored on this article, X cells symbolize a groundbreaking leap ahead in regenerative drugs, providing hope for these fighting power ache, degenerative circumstances, and age-related decline.

Not like conventional stem cell therapies, X cells harness the total energy of adipose tissue’s numerous mobile ecosystem, offering a “complete meals” strategy to therapeutic that far surpasses the capabilities of remoted or culture-expanded cells.

The outstanding survival charges of X cells — lasting weeks as an alternative of hours — mixed with their capacity to thrive in harsh environments, make them an absolute game-changer within the area. From orthopedic accidents to neurological issues, and from autoimmune circumstances to sexual well being, X cells are opening new avenues for remedy that have been beforehand unimaginable.

However the potential of X cells does not cease there. By combining this cutting-edge remedy with “stem-hacking” strategies just like the Pink, Blue, O2 protocol and focused dietary help, you’ll be able to additional amplify your physique’s innate therapeutic talents. This synergistic strategy not solely enhances the effectiveness of stem cell remedies but additionally promotes general mobile well being and longevity.

In case you are a affected person fascinated about discovering out if X cells would possibly enable you with a well being subject, otherwise you’re a healthcare supplier and also you’d like to seek out out in the event you would possibly qualify to be one in every of a restricted variety of clinics offering X cell know-how, please contact Dr. Lieurance and his crew by way of e-mail at [email protected] or go to www.xcell.us. 

To find extra about the entire modern rejuvenating practices and longevity-enhancing strategies Dr. Lieurance practices, you can even take a look at our podcasts collectively:

• Loopy Prostate Injections, Cranium-Cracking Nasal Changes, Defying Illness, Revitalizing Cells, And Safeguarding Your Sexuality With Dr. John Lieurance
• “The Loopy Future Of Medical Biohacking: Cranium Resets, Suppositories, Nasal Sprays, Nebulizers, Sound Remedy & Extra With Dr. John Lieurance. [Best of BGF]”
• “The ‘Dr. Unusual’ Of Medication & Biohacking: Methylene Blue, Stem Cells, Lasers, Earth, Air, Water, Hearth & Extra With Dr. John Lieurance.”
• “The Surprising Reality About Excessive-Dose Melatonin, Does Melatonin Supplementation Shut Down Your Personal Manufacturing, How To Use Melatonin To Improve Fasting & A lot Extra With Dr. John Lieurance.”

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• Ibid.
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