Nasal spray for OSA, lawsuit filed in opposition to FDA

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Healio has compiled the most-read information in pulmonology posted in April.

Highlights embody a nasal spray remedy that lessened sleep apnea severity in sufferers who achieved higher airway collapsibility enchancment; a lawsuit filed in opposition to the FDA over inaction on banning menthol cigarettes; findings from the American Lung Affiliation’s 2024 State of the Air report; a examine exhibiting that recurring waterpipe people who smoke had elevated blood strain and coronary heart charge following 30-minute use; various pulmonary arterial hypertension traits, mortality and remedy throughout U.S. census areas; and extra.



Photo of woman using nasal spray

Healio Pulmonology’s most-read information story of April was on a nasal spray remedy that lessened sleep apnea severity in sufferers who achieved higher airway collapsibility enchancment. Picture: Adobe Inventory

Learn these and different prime tales in pulmonology beneath:

Nasal spray remedy lessens sleep apnea severity in choose sufferers

Sufferers with obstructive sleep apnea who achieved higher airway collapsibility enchancment with a drug administered through nasal spray additionally had decrease illness severity after use of the spray, in accordance with outcomes printed in American Journal of Physiology Coronary heart and Circulatory Physiology. Learn extra.

Lawsuit filed in opposition to FDA over inaction on banning menthol cigarettes

Three well being teams have filed a lawsuit in opposition to the FDA over a delay in finalizing the proposed rule banning menthol cigarettes, in accordance with a press launch from one of many teams. Additionally, Albert Rizzo, MD, FACP, of the American Lung Affiliation, shares his Perspective. Learn extra.

2024 State of the Air report: 39% of Individuals breathe polluted, unhealthy air each day

Implementing the current stronger normal for effective particulate air pollution revealed that 131 million Individuals breathe unhealthy, polluted air the place they stay, in accordance with a press launch from the American Lung Affiliation. Learn extra.

Waterpipe smoking session heightens blood strain, coronary heart charge in recurring customers

Amongst recurring waterpipe people who smoke, brachial and aortic blood strain, in addition to coronary heart charge, rose after 30-minute outside use of the pipe, in accordance with outcomes printed in CHEST. Additionally, Christy Sadreameli, MD, MHS, nationwide volunteer medical spokesperson for the American Lung Affiliation, shares her Perspective. Learn extra.

Pulmonary arterial hypertension traits, mortality range throughout US

Amongst adults with pulmonary arterial hypertension, affected person traits, mortality and remedy assorted throughout 4 U.S. census areas, in accordance with outcomes printed in Annals of the American Thoracic Society. Learn extra.

Q&A: Uncovering why individuals develop acute respiratory misery syndrome

The rationale behind acute respiratory misery syndrome improvement in some sufferers struggling with extreme respiratory sickness and never others is unknown, however current analysis suggests a attainable rationalization. Healio spoke with Joseph Zasadzinski, PhD, of the College of Minnesota, to study extra. Learn extra.

Ensifentrine improves outcomes in COPD, however unlikely to be value efficient

When added to upkeep remedy for reasonable to extreme COPD, ensifentrine improves lung perform and exacerbation charge vs. placebo, in accordance with a draft proof report by the Institute for Medical and Financial Evaluation. Additionally, Mike Hess, MPH, RRT, RPFT, of the COPD Basis, shares his Perspective. Learn extra.

On-line inhaler approach assets usually overlook crucial steps

Web sites centered on inhaler approach incessantly overlook vital preparation steps and system care/upkeep, in accordance with outcomes printed in Respiratory Drugs. Additionally, Tori Martel, MPH, of the Allergy and Bronchial asthma Community, shares her Perspective. Learn extra.

Native air pollution elevate asthma-related ED go to charge, could contribute to disparities

Bronchial asthma-related ED go to charges rose with publicity to native effective particulate matter, coarse particulate matter and sulfur dioxide, in accordance with outcomes printed in American Journal of Respiratory and Vital Care Drugs. Learn extra.

Race-neutral lung perform equations impression spirometry interpretation

Use of race-neutral vs. race-specific lung perform equations led to totally different interpretations of spirometry findings, particularly amongst Black people, in accordance with outcomes printed in American Journal of Respiratory and Vital Care Drugs. Additionally, J. Henry Brems, MD, MBE, of Johns Hopkins College Faculty of Drugs, shares his Perspective. Learn extra.

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